ProAssurance (PRA) and Optinose (OPTN) soar on M&A news


It turns out the fastest way to please investors this week was to get acquired. That became clear on Thursday, when the day’s two biggest gainers were both companies announcing acquisition deals.

Optinose Inc. (OPTN) surged 52.5% after agreeing to be acquired by privately held Paratek Pharmaceuticals in a deal worth up to $330 million.

Optinose, which makes XHANCE — a treatment for chronic rhinosinusitis (CRS) — specializes in therapies for patients seen by ENT and allergy specialists.

Paratek will pay $9 per share in cash, a 50% premium to Wednesday’s closing price. On top of that, shareholders will receive contingent value rights worth up to $5 per share tied to future XHANCE sales, bringing the deal’s total potential value to $14 a share.

“Paratek, with its robust commercial and medical capabilities, has the potential to rapidly extend awareness of XHANCE to primary care providers who treat the majority of patients with CRS,” Optinose CEO Ramy Mahmoud said in a statement.

“We’re excited about the many ways this transaction creates opportunities for XHANCE to help more patients while creating near- and long-term value for Optinose’s shareholders.”

Optinose canceled its Q4 earnings call that had been scheduled for Thursday. The deal is expected to close mid-year.

Meanwhile, ProAssurance Corp. (PRA), a provider of medical professional liability insurance, jumped 48.1% after announcing its acquisition by The Doctors Company—the largest physician-owned medical malpractice insurer in the U.S.

ProAssurance shareholders will receive $25 per share in cash, a 60% premium to the March 18 closing price. That was the last full trading day before the deal was announced.

The total value of the deal is approximately $1.3 billion. The combined company will hold roughly $12 billion in assets.

ProAssurance’s core business includes medical liability, workers’ compensation, and product liability insurance for the medical tech and life sciences industries,

“This transaction will deliver significant value to our shareholders,” said ProAssurance CEO Ned Rand. “Both ProAssurance and The Doctors Company were founded by physicians during the medical liability crisis of the 1970s. We’ve each grown by bringing together other physician-founded companies.”

The deal still needs shareholder approval and is expected to close in the first half of 2026.

One more name worth flagging: NanoVibronix Inc. (NAOV), which acquired ENvue Medical Holdings Corp. last month, finished Thursday with the fourth-highest gains. NAOV stock jumped 36.5% for the day.


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